Monday, January 29, 2024

Possible mechaniism for the reversal of dementia. revealed in bird brain!


Black-capped chickadee grows brain cells to remember where it stashed its food!




https://www.ndtv.com/science/popular-bird-species-grows-brain-tissues-to-survive-brutal-winter-3676917#:~:text=According%20to%20National%20Library%20of%20Medicine%20%28NLM%29%20of,winter%20as%20does%20the%20rate%20of%20hippocampal%20neurogenesis.

 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830249/



Environmenta! cues/stimuli (e.g. shortening daylight) activate a genetic program wch triggers a biochemiical chain of reactions culminating in the activation of dormant stem cells in. the hippocampus.
"Brain-derived Neurotropic factor" stimulates cell growth in hippocampus --(-the structure of the brain that encodes and stores experience into memories) resulting in a 30% increase in the size of the hippocampus!
If the sequence of. molecular events underlying this process can be understood, it may be similarly activated in the brains of persons with dementia where the hippocampus has atrophied and memory creation and retrieval have been compromised! ...thereby reversing memory and cognitive impairment